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Repeated use of the same site can cause lipohypertrophy or tissue changes that increase discomfort

Archived (PDF) from the original on 16 April 2021

Oral Facial Pain Headache 31 , 240250 (2017)

Common effects include: Nausea or stomach upset Constipation or diarrhea Vomiting in rare cases Reduced appetite In most cases, these effects decrease after several weeks